Publicaciones

  • Metronomic chemotherapy response in triple-negative MDA-MB-231 breast cancer cells under nicotine exposure. Español A, Sanchez Y, Volpi S. BioCell. 49 (8):1449-1480. 2025. doi.org/10.32604/biocell.2025.068034
  • Imidacloprid actions in the mouse mammary gland structure and epithelial mammary cells. Role of GPER and nAChR. Leguizamón MA, Buján S, Sánchez Y, Pontillo C, Chiappini F, Español A, Randi A, Miret N. Environmental Research. 2025. doi.org/10.1016/j.envres.2025.122620
  • Hexachlorobenzene as a differential modulator of the conventional and metronomic chemotherapy response in triple negative breast cancer cells”. Sanchez Y, Vasquez A, Miret N, Rolandelli G, Costas C, Randi A, Español A. Exploration of Targeted Anti-tumor Therapy. 5: 278-295. DOI: 10.37349/etat.2024.00218
  • Nicotinic receptors modulate antitumor therapy response in triple negative breast cancer cells. Español A, Sanchez Y, Salem A, Obregon J, Sales M. World Journal of Clinical Oncology. 13(6): 505-519. DOI: 10.5306/wjco.v13.i6.505
  • Human Breast Tumour Effect Cells Viability of African Dioscorea rotundata Tuber Extracts in MCF-7 and MDA-MB231 Cell Lines”. JI Odimegwu, OA Odukoya, A Español, ME Sales. Reports in Cancer and Treatment. 6(2). doi: 10.4172/Rep cancer Treat.6.2.001
  • Breast cancer: muscarinic receptors as new targets for tumor therapy. Español A, Salem A, Sanchez Y, Sales M. World Journal of Clinical Oncology. 12(6):404-428. doi: 10.5306/wjco.v12.i6.404
  • The metronomic combination of cholinergic agonists plus paclitaxel inhibits triple negative breast tumor progression: participation of M2 receptor subtype”. Español A, Di Bari M, Salem A, Cristofaro I, Sanchez Y, Tata A, Sales M. PlosOne. 2020. 15(9):e0226450. doi: 10.1371/journal.pone.0226450. eCollection 2020.
  • Effect of low dose metronomic therapy on MCF-7 tumor cells growth and angiogenesis. Role of muscarinic acetylcholine receptors. Agustina Reina Salem, Paola Martinez, Francisco Sanchez, Yamila Sanchez, Alejandro Español, María Sales. Int Immunol. 2020. Apr 17;84:106514. doi: 10.1016/j.intimp.2020.106514.
  • Breast cancer angiogenesis induced by pesticide ligands of aryl hydrocarbon receptor hexachlorobenzene and chlorpyrifos. Zárate, Lorena; Pontillo, Carolina; Español, Alejandro; Miret, Noelia; Chiappini, Florencia; Cocca, Claudia; Álvarez, Laura; Kleiman de Pisarev, Diana; Sales, María Elena; Randi, Andrea S. Toxicol Appl Pharmacol. Jun 8;115093. doi: 10.1016/j.taap.2020.115093.
  • Role of Muscarinic Acetylcholine Receptors in Breast Cancer: Design of Metronomic Chemotherapy. Sales ME, Español AJ, Salem AR, Pulido PM, Sanchez Y, Sanchez F. Curr Clin Pharmacol. 2019;14(2):91-100. doi: 10.2174/1574884714666181203095437.
  • Denatonium and Naringenin Promote SCA-9 Tumor Growth and Angiogenesis: Participation of Arginase. Dmytrenko G, Castro ME, Sales ME. Nutr Cancer. 2017 Jul;69(5):780-790. doi: 10.1080/01635581.2017.1328605.
  • Muscarinic Receptors as Targets for Metronomic Therapy in Breast Cancer. Sales ME. Curr Pharm Des. 2016;22(14):2170-7. doi: 10.2174/1381612822666160229115317
  • Cholinergic actions of autoantibodies from breast cancer patients on dendritic cells. Lombardi G, Salamone G, Gori S, Oroño M, Español A, Sales M. J of Clin & Cell Immunol. http://dx.doi.org/10.4172/2155-9899.1000340. 2015
  • Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC-1”. Pontillo C, Español AJ, Chiappini F, Miret N, Cocca C, Alvarez L, Kleiman D, Sales M, Randi A. Toxicological Sciences. Vol 239: 53-64. 2015.
  • Participation of non-neuronal muscarinic receptors in the effect of carbachol with paclitaxel on human breast adenocarcinoma cells. Roles of nitric oxide synthase and arginase.”. Español AJ, Salem A, Rojo D, Sales M. International Immunopharmacology. S1567-5769(15)00120-4. doi: 10.1016. 2015.
  • Treatment with LPS plus INF-γ induces the expression and function of muscarinic acetylcholine receptors, modulating NIH3T3 cell proliferation: participation of NOS and COX”. Español AJ, Maddaleno M, Lombardi M, Cella M, Pulido P, Sales M. Br J Pharmacol. Vol 171(22):5154-67. 2014.
  • The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy.”. Orqueda AJ, Dansey MV, Español A, Veleiro AS, Bal de Kier Joffé E, Sales ME, Burton G, Pecci A. Biochem Pharmacol. Vol 89(4):526-35. 2014.
  • Muscarinic activation enhances the anti-proliferative effect of paclitaxel in murine breast tumor cell”. Español AJ, Jacob G, Dmytrenko G, Sales ME. Anti-Cancer Agents in Medicinal Chemistry. Vol 13(8): 1273-1279. 2013
  • Cholinergic drugs as therapeutic tools in inflammatory diseases: participation of neuronal and non-neuronal cholinergic systems. Sales ME. Antiinflamm Antiallergy Agents Med Chem. 2013;12(2):109-16. doi: 10.2174/1871523011312020002
  • Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. Lombardi MG, Negroni MP, Pelegrina LT, Castro ME, Fiszman GL, Azar ME, Morgado CC, Sales ME. PLoS One. 2013;8(2):e57572. doi: 10.1371/journal.pone.0057572.
  • Macrophages derived from septic mice modulate nitric oxide synthase and angiogenic mediators in the heart.de la Torre E, Hovsepian E, Penas FN, Dmytrenko G, Castro ME, Goren NB, Sales ME. J Cell Physiol. 2013 Jul;228(7):1584-93. doi: 10.1002/jcp.24320.
  • Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors. Pelegrina LT, Lombardi MG, Fiszman GL, Azar ME, Morgado CC, Sales ME. J Clin Immunol. 2013 Feb;33(2):427-35. doi: 10.1007/s10875-012-9804-y
  • Muscarinic regulation of SCA-9 cells proliferation via nitric oxide synthases, arginases and cyclooxygenases. Role of the nuclear translocation factor-kB”. Español AJ, Dasso M, Goren N, Sales ME European Journal of Pharmacology. Vol 683(1-3):43-53. 2012.
  • Immunoglobulin g from breast cancer patients regulates MCF-7 cells migration and MMP-9 activity by stimulating muscarinic acetylcholine receptors. Pelegrina LT, Lombardi MG, Fiszman GL, Azar ME, Morgado CC, Sales ME. J Clin Immunol. 2013 Feb;33(2):427-35. doi: 10.1007/s10875-012-9804-y.